With the development of foam drainage gas recovery technology in the Sulige field, the problem of foam affecting the downstream is gradually becoming prominent. Therefore, we carry out field experiment of defoaming process in gas gathering station. Experiment results which the solid defoaming device is installed before the first stage separator showed that the liquid defoaming agent need daily filling, FG-4 two solid defoamer 3-6 days;the average natural defoaming time of the liquid defoaming and solid defoamer was 6 minutes and 3 - 4 minutes respectively;the average foam suppression test time of liquid defoaming agent and solid defoaming agent was refoaming 1 minute later and without foam accumulation respectively. Natural defoaming and foam suppression of the solid defoaming agent have good utilize effect. There are two stage separators in the partial gas gathering station. Improved experiment which the solid defoaming device is installed between the first stage and the two stage separator showed that the defoaming agent is added once every 39 days, which can effectively reduce the consumption of defoaming agent. The solid defoaming device runs smoothly and relatively save manpower and material resources. The cost is reduced with the improvement of the process, and the application prospect is better.